Single-cell Elemental Analysis Using Inductively Coupled Plasma Mass Spectrometry (ICP-MS)
2025.01.22
Inductively coupled plasma mass spectrometry (ICP-MS) is prominently used for analyzing elemental composition in individual cells. However, the conventional sample introduction system of ICP-MS causes damage to large mammalian cells. Now, researchers from Japan suggest an efficient method of introducing mammalian cells using a microdroplet generator (µDG) that maintains the cell's structure without compromising elemental composition. These findings can open new avenues for the diagnosis and prognosis of diseases.